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1.
Dev Psychol ; 2024 Mar 28.
Artículo en Inglés | MEDLINE | ID: mdl-38546570

RESUMEN

Little is known about how perfectionistic adolescents experience social connection in online spaces. The current qualitative study addressed this gap by examining themes related to social (dis)connection in online and in-person settings from semistructured interviews with 43 adolescents (Mage = 15.16, SD = 2.43; 62.8% female; 58.1% white; 54.4% self-identified perfectionists). Results demonstrated that perfectionists expressed feeling less connected online than nonperfectionists, likely driven by heightened levels of interpersonal sensitivity. However, a subgroup of perfectionists sought out meaningful online relationships, often in response to a fear or experience of rejection by in-person peers. The results highlight the role of interpersonal sensitivity in fueling feelings of disconnection among adolescent perfectionists in both online and in-person settings, as well as the importance of self-monitoring in the social experiences of perfectionistic youth. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

2.
J Pers Assess ; : 1-13, 2024 Jan 25.
Artículo en Inglés | MEDLINE | ID: mdl-38271468

RESUMEN

This article introduces a measure of self-condemnatory internal dialogue as an element of the relationship with the self: The Automatic Self-Recrimination Scale (ASRS). Using the construct validation approach to test construction, we describe the initial development of items and report on findings from a clinical and nonclinical sample showing the ASRS is best understood as a multidimensional measure of self-critical internal dialogue composed of one higher-order factor and four lower-order facets: Not Mattering, Self as Failure, Undeserving Self, and Loathsomeness. The overall scale and four subscales demonstrated acceptable internal consistency and test-retest reliability. Moreover, there was evidence of good convergent and incremental validity of the ASRS subscales with measures of perfectionism, self-criticism, and dysfunctional attitudes. Overall, the ASRS appears to be a reliable and valid measure of an automatic self-recriminatory internal dialogue.

3.
Neurotoxicol Teratol ; 95: 107134, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-36395973

RESUMEN

BACKGROUND: Exposure to tobacco and cannabis during developmental periods of enhanced vulnerability (e.g., in utero and early childhood) may have long-lasting effects on child health. One potential mechanism underlying these associations is the alteration of inflammatory pathways. Using data from a longitudinal study of mother/child dyads, we examined the adjusted and combined associations of prenatal and postnatal tobacco and cannabis exposure with inflammation in early childhood. Furthermore, we explored the relations between different measures of exposure, partly reflecting differences in timing, dose, and level of fetal exposure (e.g., self-report vs. biomarker), and inflammation. Finally, we explored child sex as a moderator of prenatal and postnatal tobacco and cannabis exposure and inflammation. METHOD: Women were recruited from a local hospital during their first prenatal appointment. Repeated assessments were conducted at each trimester, at birth, and when children were 2, 9, 16, 24, 36, and 60 months old (N = 215; 112 female children). To evaluate associations with different measurement approaches, prenatal tobacco and cannabis exposure were assessed using: 1) continuous dose-response variables of maternal self-reported tobacco and cannabis use during each trimester to assess associations with timing and severity of exposure, 2) categorization of children into exposure groups based on drugs and metabolites present in infant meconium reflecting later pregnancy fetal exposure, and 3) categorization into exposure groups using a combination of maternal self-report data and biomarker data derived from maternal saliva samples and infant meconium taking advantage of multiple methods of assessment to examine group differences. Postnatal exposure to tobacco (assessed using child salivary cotinine) and cannabis (assessed using maternal self-reported average joints smoked per day) was measured at each infancy/early childhood assessment. Adjusted pre- and postnatal exposure associations with child inflammation were assessed by including both measures as predictor variables in linear regression models predicting child salivary C-reactive protein (CRP) concentrations at 60 months. Interactions between pre- and postnatal exposure variables were then modeled to investigate the combined relations between pre- and postnatal substance exposure with child salivary CRP concentrations at 60 months. RESULTS: Adjusting for postnatal exposure variables, there was a significant interaction between the average daily cigarettes and the average daily cannabis joints smoked during the third trimester predicting salivary CRP concentrations in early childhood. At high tobacco exposure, the effect of cannabis on CRP concentrations was negligible, whereas at low tobacco exposure, the effect of cannabis exposure on CRP concentrations was positive. Adjusting for postnatal tobacco and cannabis exposure, children for whom meconium data indicated co-exposure to tobacco and cannabis showed approximately 43% lower CRP concentrations at age 60 months compared to children with no exposure. However, when mother/child dyads were categorized based on a combination of maternal self-report data and biomarker data from saliva samples and infant meconium, there were no differences in salivary CRP concentrations at age 60 months across the three groups (no prenatal exposure, prenatal tobacco exposure only, prenatal co-exposure to tobacco and cannabis), controlling for postnatal associations. Regardless of the measurement method used to assess prenatal exposures in adjusted analyses, prenatal tobacco exposure alone did not predict CRP concentrations in early childhood, nor did postnatal tobacco exposure. Among boys, postnatal cannabis exposure was associated with higher concentrations of CRP at age 60 months, controlling for prenatal exposure relations. There were no significant combined associations of pre- and postnatal exposure with CRP concentrations. CONCLUSION: This study expands upon known relations between prenatal and postnatal substance exposure and immunological outcomes in early childhood, underscoring the importance of assessing cannabis exposure during gestation and early life in combination with tobacco exposure.


Asunto(s)
Cannabis , Efectos Tardíos de la Exposición Prenatal , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Embarazo , Biomarcadores/análisis , Proteína C-Reactiva/análisis , Cannabis/efectos adversos , Inflamación , Estudios Longitudinales , Efectos Tardíos de la Exposición Prenatal/metabolismo , Nicotiana
4.
Child Dev ; 94(1): 254-271, 2023 01.
Artículo en Inglés | MEDLINE | ID: mdl-36131681

RESUMEN

This prospective longitudinal study evaluated changes in psychological distress among adolescents, pre-pandemic to intra-pandemic, the extent to which within-person and between-person differences in trait multidimensional perfectionism were associated with such changes, and the role of stress in explaining associations between perfectionism and psychological distress. Adolescents (N = 187; 80% female; 78% White, 7% Asian Canadian, 2% Indigenous Peoples in Canada, 2% Black or African Canadian, 2% Latin Canadian, or 9% Other; Mage  = 17.96 years) completed online surveys assessing perfectionism (i.e., self-oriented perfectionism and socially prescribed perfectionism), depression, anxiety, and stress pre-pandemic (i.e., March 12, 2020 or earlier) and during Ontario, Canada's first (i.e., March 13, 2020 to July 24, 2020) and second (December 26, 2020 to February 7, 2021) government-mandated lockdowns. Between-person differences and within-person changes in multidimensional trait perfectionism were associated with increases in psychological distress and perceived stress. Perceived stress served as an intermediary pathway linking multidimensional trait perfectionism to psychological distress during the pandemic.


Asunto(s)
COVID-19 , Perfeccionismo , Distrés Psicológico , Humanos , Femenino , Adolescente , Masculino , Pandemias , Estudios Longitudinales , Estudios Prospectivos , Control de Enfermedades Transmisibles , Ontario/epidemiología , Autoimagen
5.
Brain Behav Immun Health ; 25: 100516, 2022 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-36177305

RESUMEN

Adverse childhood experiences (ACEs) are associated with dysregulation of inflammation and cortisol. The objectives of this study were to use principal component analysis to explore the inflammatory biomarker data to create inflammation composite variables; to examine the relationship between these composite measures of inflammation with ACEs and cortisol; and to assess whether these relationships were moderated by sex. The analysis included 232 young adults from the Niagara Longitudinal Heart Study (NLHS). After adjusting for covariates, higher exposure to ACEs significantly predicted higher low-grade inflammation. These results further support the use of multiple biomarkers to understand the complex relationships among ACEs, cortisol, and inflammation, which should be further examined in longitudinal studies to study biomarker trajectories.

6.
Pers Individ Dif ; 189: 111492, 2022 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-35001996

RESUMEN

The current work provides a multi-methods exploration of how within-person subtypes of self-oriented perfectionism (SOP) and socially prescribed perfectionism (SPP) were related to shifts in health-promoting behaviors among adolescents following the onset of the COVID-19 pandemic. Study One tested the 2 × 2 and tripartite models of perfectionism through a quantitative test of how such subtypes predicted changes in health behaviors pre-pandemic to intra-pandemic among 202 adolescents (M = 17.86, SD = 1.421). Results indicated that the combination of high SOP/high SPP was linked to the most maladaptive changes to health-promoting behaviors, supporting the tripartite model. Study Two aimed to contextualize these findings by analyzing semi-structured interviews with 31 adolescent self-identified perfectionists (M = 15.97, SD = 1.991) during the initial lockdown mandate. Results indicated that participants experienced a welcome break and found more time to engage in health-promoting behaviors. However, those high in SOP - regardless of their level of SPP - had more difficulty relaxing due to a resistance to relenting their perfectionistic standards. Altogether, these findings support the exacerbating role of SOP when combined with SPP posited by the tripartite model of perfectionism with respect to adolescents' health-promoting behaviors during the COVID-19 pandemic.

7.
J Ration Emot Cogn Behav Ther ; 40(3): 474-492, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-34690428

RESUMEN

This study employed a two-wave cross-lagged panel analysis to examine associations between perfectionistic cognitions, anxiety, and depression pre-pandemic to during the pandemic in a sample of 171 (57% female, n = 98) emerging adults. Results demonstrated that perfectionistic cognitions decreased, anxiety increased, and depressive symptoms did not change pre-pandemic to during the pandemic. Cross-lagged results indicated that pre-pandemic perfectionistic cognitions predicted higher levels of anxiety symptoms (but not depressive symptoms) during the pandemic after accounting for pre-pandemic levels of anxiety and depressive symptoms. These results held with the inclusion of covariates (i.e., sex, age, education, exposure to COVID-19, whether or not participants knew someone diagnosed with COVID-19, had lost income due to the pandemic, and how often they thought about COVID-19). Psychological distress (i.e., anxiety and depressive symptoms) pre-pandemic did not predict perfectionistic cognitions during the pandemic after accounting for pre-pandemic levels of perfectionistic cognitions. Results support assertions that individuals with heightened levels of perfectionism are at an increased risk for poorer mental health during the pandemic. Findings underscore the importance of assessing perfectionistic cognitions for the prevention and treatment of anxiety symptoms among emerging adults during and post-pandemic.

8.
Brain Behav Immun Health ; 13: 100211, 2021 May.
Artículo en Inglés | MEDLINE | ID: mdl-34589737

RESUMEN

Previous research has demonstrated that perfectionism is implicated in poorer health and earlier mortality. However, to our knowledge, research has not yet determined how individual differences in perfectionistic cognitions are related to intermediary health markers such as inflammation. Thus, within the theoretical frameworks of the perfectionism diathesis-stress model (Hewitt and Flett, 1993) and the cognitive theory of perfectionism (Flett et al., 2018; Flett et al., 2016) the aims of our study were to test whether individual differences in perfectionistic cognitions were associated with low-grade inflammation via c-reactive CRP and IL-6 biomarkers and whether these relationships varied as a function perceived stress. The sample included 248 Canadian young adults (52% female, Mage â€‹= â€‹22.89, SD â€‹= â€‹1.53) who completed surveys assessing key constructs such as perfectionistic cognitions and perceived stress along with providing assessments of body fat percentage and serum samples of IL-6 and CRP. Regression analyses indicated that perfectionistic cognitions were not related to IL-6 under any conditions of stress. However, under high levels of stress perfectionistic cognitions were associated with elevated levels of CRP and these findings held after accounting for the effects of smoking status, body fat percentage, and respondent sex. The present work adds to the growing body of evidence supporting links between personality and inflammation. These findings raise the possibility that experiencing more frequent thoughts centered on the need to be perfect when coupled with higher levels of stress may set the stage for greater vulnerability for chronic inflammation.

9.
J Sport Exerc Psychol ; 43(3): 234-247, 2021 06 01.
Artículo en Inglés | MEDLINE | ID: mdl-33894693

RESUMEN

This study provided the first test of the 2 × 2 model of perfectionism with respect to dancers' goals for dancing in competitive dance. Four hundred twenty-five young female North American competitive dancers (M = 11.33 years; SD = 2.14) completed questionnaires assessing multidimensional perfectionism and goals for participation in dance. The latent moderated structural equations approach along with procedures outlined by Gaudreau indicated partial support for the 2 × 2 model of perfectionism. Pure Evaluative Concerns Perfectionism was associated with fewer intrinsic goals for dance and greater extrinsic goals for dance relative to nonperfectionism. Pure Personal Standards Perfectionism was related to less endorsement of extrinsic goals relative to nonperfectionism. Findings were complex with respect to mixed perfectionism, with this form of perfectionism being related to greater endorsement of both intrinsic and extrinsic goals for dance. Results provide partial support for the 2 × 2 model in youth dance.


Asunto(s)
Baile , Perfeccionismo , Adolescente , Femenino , Objetivos , Humanos , Encuestas y Cuestionarios
10.
Int J Ment Health Addict ; 19(6): 2204-2218, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-32837419

RESUMEN

In this study, we sought to examine associations between dimensions of trait perfectionism and posttraumatic stress disorder (PTSD) symptoms among a community sample of adults who experienced at least one traumatic event and determine whether the associations between trait perfectionism dimensions and PTSD symptomatology varied as a function of perceived control. A sample of 161 (57% women; M = 33.24 years, SD = 10.84 years) community adults who experienced at least one traumatic event in their lives completed self-report measures of trait perfectionism, perceived control, personality, and PTSD symptomatology. Results from multiple regression analyses indicated that socially prescribed perfectionism was associated with higher levels of PTSD symptomatology. However, this finding was qualified by a significant interaction with perceived control such that higher levels of socially prescribed perfectionism were associated with greater PTSD symptomatology only under conditions of low perceived control. Findings underscore the importance of individual differences in socially prescribed perfectionism and perceived control for PTSD symptomatology.

11.
Infant Ment Health J ; 41(4): 530-542, 2020 07.
Artículo en Inglés | MEDLINE | ID: mdl-32594565

RESUMEN

The purpose of this study was to examine the moderating role of maternal sensitivity on the association between prenatal adversity and externalizing behaviors at 24 months of age in a diverse, high-risk sample. We hypothesized that among children with higher prenatal adversity, high maternal sensitivity would serve as a protective factor. Participants were 247 primarily low-income, diverse dyads. Results indicated a significant interaction effect of maternal sensitivity and prenatal adversity on externalizing problems. The association between prenatal adversity and externalizing behaviors was significant only among children who experienced low prenatal adversity, with higher maternal sensitivity associated with lower externalizing behaviors. These findings indicate that, in the absence of high prenatal risk, responsive and sensitive parenting can buffer children in an otherwise high-risk sample from the development of externalizing behaviors.


El propósito de este estudio fue examinar el papel moderador que la sensibilidad materna tiene sobre la asociación entre adversidad prenatal y las conductas de externalización a los 24 meses de edad en un grupo muestra diverso y de alto riesgo. Nuestra hipótesis es que entre los niños con más alta adversidad prenatal (PA), una alta sensibilidad materna serviría como un factor de protección. Participaron 247 díadas diversas, primariamente de bajos recursos económicos (173 infantes expuestos a sustancias). Los resultados indicaron un significativo efecto de interacción de la sensibilidad materna y la adversidad prenatal sobre los problemas de externalización. La asociación entre la adversidad prenatal y las conductas de externalización fue significativa sólo entre niños que habían experimentado una adversidad prenatal baja, mientras que una más alta sensibilidad materna se asoció con más bajas conductas de externalización. Estos resultados indican que, en ausencia de un riesgo prenatal alto, una crianza receptiva y sensible puede amortiguar el desarrollo de conductas de externalización en niños que, de lo contrario, están dentro de un grupo muestra de alto riesgo.


Le but de cette étude était d'examiner le rôle modérateur de la sensibilité maternelle sur l'association entre l'adversité prénatale et les comportements d'externalisation à l'âge de 24 mois chez un échantillon varié, et à haut risque. Nous avons pris comme hypothèse que chez les enfants avec une adversité prénatale élevée (PA), une sensibilité maternelle élevée servirait de facteur de protection. Les participants ont consisté en 247 dyades diverse et principalement issues de milieux défavorisés (173 bébés exposés à la toxicomanie). Les résultats indiquent un effet d'interaction important de la sensibilité maternelle et de l'adversité prénatale sur les problèmes d'externalisation. Le lien entre l'adversité prénatale et les comportements d'externalisation n'était important que chez les enfants ayant fait l'expérience d'une adversité prénatale peu élevée, avec une sensibilité maternelle plus élevée liée à des comportements d'externalisation moins élevés. Ces résultats indiquent que, en l'absence d'une risque prénatal élevé, le parentage réactif et sensible peut servir de tampon aux enfants contre le développement de comportements d'externalisation dans un échantillon qui est par ailleurs à haut risque.


Asunto(s)
Trastornos de la Conducta Infantil/psicología , Responsabilidad Parental/psicología , Pobreza/psicología , Efectos Tardíos de la Exposición Prenatal/psicología , Ira , Preescolar , Depresión/psicología , Femenino , Humanos , Masculino , Embarazo , Factores de Riesgo
12.
Dev Psychopathol ; 32(1): 85-103, 2020 02.
Artículo en Inglés | MEDLINE | ID: mdl-30704548

RESUMEN

This study investigated the longitudinal associations among prenatal substance use, socioeconomic adversity, parenting (maternal warmth, sensitivity, and harshness), children's self-regulation (internalization of rules and conscience), and conduct problems from infancy to middle childhood (Grade 2). Three competing conceptual models including cascade (indirect or mediated), additive (cumulative), and transactional (bidirectional) effects were tested and compared. The sample consisted of 216 low-income families (primary caretaker and children; 51% girls; 74% African American). Using a repeated-measures, multimethod, multi-informant design, a series of full panel models were specified. Findings primarily supported a developmental cascade model, and there was some support for additive effects. More specifically, maternal prenatal substance use and socioeconomic adversity in infancy were prospectively associated with lower levels of maternal sensitivity. Subsequently, lower maternal sensitivity was associated with decreases in children's conscience in early childhood, and in turn, lower conscience predicted increases in teacher-reported conduct problems in middle childhood. There was also a second pathway from sustained maternal depression (in infancy and toddlerhood) to early childhood conduct problems. These findings demonstrated how processes of risk and resilience collectively contributed to children's early onset conduct problems.


Asunto(s)
Trastornos de la Conducta Infantil/etiología , Hijo de Padres Discapacitados/psicología , Conciencia , Depresión/psicología , Madres/psicología , Pobreza/psicología , Trastornos Relacionados con Sustancias/psicología , Niño , Conducta Infantil/psicología , Trastornos de la Conducta Infantil/psicología , Desarrollo Infantil/fisiología , Preescolar , Femenino , Humanos , Lactante , Masculino , Embarazo , Problema de Conducta/psicología , Factores de Riesgo
13.
BMJ Open ; 9(7): e030339, 2019 07 16.
Artículo en Inglés | MEDLINE | ID: mdl-31315878

RESUMEN

INTRODUCTION: Recent reviews have found substantial links between a toxic childhood environment including child abuse and severe household dysfunction and adult cardiovascular disease (CVD). Collectively referred to as adverse childhood experiences (ACEs), this toxic environment is prevalent among children, with recent Canadian estimates of child abuse at 27%-32%, and severe household dysfunction at 49%. Based on these prevalence rates, the potential effect of ACEs on CVD is more significant than previously thought. Yet, how ACEs amplify the risk for later CVD remains unclear. Lifestyle risk factors only partially account for this connection, instead directing attention to the interaction between psychosocial factors and physiological mechanisms such as inflammation. The Niagara Longitudinal Heart Study (NLHS) examines how ACEs influence cardiovascular health (CVH) from childhood to early adulthood. Integrating the stress process and biological embedding models, this study examines how psychosocial and physiological factors in addition to lifestyle factors explain the relationship between ACEs and CVH. METHODS: This follow-up study combines three baseline studies from 2007 to 2012 that collected CVH measures including child blood pressure, heart rate, left ventricular structure and function, arterial stiffness indices and baroreflex sensitivity on 564 children. Baseline data also include anthropometric, biological, lifestyle, behavioural, and psychosocial measures that varied across primary studies. Now over 18 years of age, we will recruit and retest as many participants from the baseline studies as possible collecting data on ACEs, CVH, anthropometric, lifestyle and psychosocial measures as well as blood, saliva and hair for physiological biostress markers. ETHICS AND DISSEMINATION: Ethics approval has been received for the NLHS follow-up. Written consent to participate in the follow-up study is obtained from each participant. Results testing all proposed hypotheses will be submitted for publication in peer-reviewed journals.


Asunto(s)
Experiencias Adversas de la Infancia , Enfermedades Cardiovasculares/epidemiología , Barorreflejo , Biomarcadores/sangre , Presión Sanguínea , Arteria Carótida Común/diagnóstico por imagen , Grosor Intima-Media Carotídeo , Frecuencia Cardíaca , Ventrículos Cardíacos/diagnóstico por imagen , Humanos , Estudios Longitudinales , Proyectos de Investigación , Encuestas y Cuestionarios , Ultrasonografía , Rigidez Vascular
14.
J Am Pharm Assoc (2003) ; 59(1): 13-16, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30348510

RESUMEN

OBJECTIVES: The Division of Drug Information (DDI) within the U.S. Food and Drug Administration's (FDA's) Center for Drug Evaluation and Research receives telephone calls, e-mails, and letters from patients and industry. The consistently high number of contacts about drugs in the fluoroquinolone class indicates an opportunity to increase awareness about the drugs' evolving safety profile. DATA SOURCES: Database used by DDI to summarize inquiries. SUMMARY: Inquiries about fluoroquinolones peaked in 2016 and were highest after FDA Drug Safety Communications that were issued that year. Among the first fluoroquinolone, ciprofloxacin, was approved in 1987. Since then, the FDA has required class-wide labeling changes reflecting postmarket benefit-risk assessments of oral and injectable (systemic) fluoroquinolones, including changes in 1990, 2008, 2013, 2016, and 2018. CONCLUSION: Pharmacists have a role that is more critical than ever to ensure the safety of patients who are prescribed a systemic fluoroquinolone. Pharmacists should stay informed on this class of drugs, be prepared to suggest alternate therapies, counsel patients on potential benefits and risks, and work with patients to submit Medwatch reports to the FDA if adverse events occur.


Asunto(s)
Bases de Datos Farmacéuticas/estadística & datos numéricos , Fluoroquinolonas/efectos adversos , Farmacéuticos , Rol Profesional , Humanos , Seguridad del Paciente , Vigilancia de Productos Comercializados/estadística & datos numéricos , Estados Unidos , United States Food and Drug Administration
15.
Neurotoxicol Teratol ; 67: 31-36, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29597003

RESUMEN

AIMS: Secretory Immunoglobulin A (SIgA) plays a critical role in immune functioning by preventing pathogens from adhering to epithelial mucosa. Most infectious agents enter the body via mucosal surfaces, thus SIgA serves in the defense against respiratory, intestinal, and urinogenitary infections, as well as periodontal disease and caries. This study examined the possibility that pre- and postnatal exposure to cigarette and cannabis is associated with individual differences in Secretory Immunoglobulin A (SIgA) levels in early childhood. METHODS: Participants were 50 mother/infant (29 boys; 35% Caucasian) dyads recruited at their first prenatal appointment in a large northeastern community hospital in the United States. Repeated assessments of pre- and postnatal cigarette and cannabis were conducted beginning in the first trimester of pregnancy, using multiple methods (i.e., saliva, meconium, self-report). Infants were grouped into those prenatally exposed to either cigarette only (n = 19), cigarette and cannabis (n = 19), or with no prenatal substance exposure (n = 12). At age 5 years, the children's saliva was collected and assayed for SIgA. RESULTS: There were group differences in SIgA levels as a function of prenatal exposure to cigarette and cannabis - children in the cigarette only and the cigarette and cannabis groups had higher SIgA levels compared to the non-exposed children. Children who experienced the combination of postnatal exposure to cigarette and cannabis had higher levels of SIgA, even after accounting for prenatal exposures and other covariates relevant to immune system functioning. CONCLUSIONS: Prenatal and postnatal exposure to cigarette and cannabis may be associated with hyperactivity of mucosal immunity in early childhood. Links between cigarette and cannabis exposure and health problems in early childhood may be partially explained by prenatal and postnatal exposure-related changes in mucosal immunity.


Asunto(s)
Cannabis/toxicidad , Inmunoglobulina A Secretora/metabolismo , Efectos Tardíos de la Exposición Prenatal/metabolismo , Saliva/metabolismo , Productos de Tabaco/toxicidad , Adolescente , Adulto , Preescolar , Interacciones Farmacológicas , Femenino , Humanos , Masculino , Embarazo , Adulto Joven
16.
J Pers Soc Psychol ; 115(3): 526-563, 2018 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-28437125

RESUMEN

Even in relatively tolerant countries, antigay bias remains socially divisive, despite being widely viewed as violating social norms of tolerance. From a Justification-Suppression Model (JSM) framework, social norms may generally suppress antigay bias in tolerant countries, yet be "released" by religious justifications among those who resist gay rights progress. Across large, nationally representative US samples (Study 1) and international samples (Study 2, representing a total of 97 different countries), over 215,000 participants, and various indicators of antigay bias (e.g., dislike, moral condemnation, opposing gay rights), individual differences in religious attendance was uniquely associated with greater antigay bias, over and above religious fundamentalism, political ideology, and religious denomination. Moreover, in 4 of 6 multilevel models, religious attendance was associated with antigay bias in countries with greater gay rights recognition, but was unrelated to antigay bias in countries with lower gay rights recognition (Study 2). In Study 3, Google searches for a religious justification ("love the sinner hate the sin") coincided temporally with gay-rights relevant searches. In U.S. (Study 4) and Canadian (Study 5) samples, much of the association between religious attendance and antigay bias was explained by "sinner-sin" religious justification, with religious attendance not associated with antigay bias when respondents reported relatively low familiarity with this justification (Study 5). These findings suggest that social divisions on homosexuality in relatively tolerant social contexts may be in large part due to religious justifications for antigay bias (consistent with the JSM), with important implications for decreasing bias. (PsycINFO Database Record


Asunto(s)
Homofobia/psicología , Derechos Humanos/psicología , Modelos Psicológicos , Religión y Psicología , Minorías Sexuales y de Género/legislación & jurisprudencia , Adulto , Femenino , Humanos , Masculino
17.
Nicotine Tob Res ; 19(5): 525-531, 2017 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-28403474

RESUMEN

INTRODUCTION: Many studies on prenatal tobacco exposure (PTE) effects have relied on single item retrospective measures of PTE. However, it is unclear how these single item measures may relate to more intensive maternal self-reports and to biological markers of maternal use and/or fetal exposure. It is also unclear whether these measures may be more valid predictors of fetal growth (gestational age, birthweight, head circumference, and birth length). METHODS: Data were obtained from 258 women during their pregnancy. PTE was assessed by four methods: a single item question, a calendar-based self-report measure from each trimester of pregnancy, maternal salivary cotinine assays, and nicotine and metabolites in infant meconium. We hypothesized that the more intensive measures and biological assays would account for additional variance in birth outcomes, above and beyond the single item measure. RESULTS: The single item self-report measure was not related to fetal growth. However, the more intensive calendar based self-report measure and the biological assays of PTE (ie, maternal salivary assays and infant meconium) were significant predictors of poor fetal growth, even with the single item measure in the model. CONCLUSIONS: The negative effects of PTE on important child outcomes may be greatly underestimated in the literature as many studies use single item self-report measures to ascertain PTE. Whereas more intensive self-report measures or biological assays may be cost prohibitive in large scale epidemiological studies, using a combination of measures when possible should be considered given their superiority both identifying prenatal smokers and predicting poor fetal growth. IMPLICATIONS: The present work underscores the importance of measurement issues when assessing associations between PTE and fetal growth. Results suggest that we may be greatly underestimating the negative effects of prenatal smoking on fetal growth and other important child outcomes if we rely solely on restricted single item self-report measures of prenatal smoking. Researchers should consider more intensive prospective self-report measures and biological assays as viable and superior alternatives to single item self-report measures.


Asunto(s)
Peso al Nacer/efectos de los fármacos , Desarrollo Fetal/efectos de los fármacos , Mujeres Embarazadas , Fumar/efectos adversos , Biomarcadores/metabolismo , Cotinina/efectos adversos , Cotinina/análisis , Cotinina/metabolismo , Femenino , Edad Gestacional , Humanos , Recién Nacido , Estudios Longitudinales , Intercambio Materno-Fetal/efectos de los fármacos , Meconio/metabolismo , Nicotina/efectos adversos , Nicotina/análisis , Nicotina/metabolismo , Embarazo , Mujeres Embarazadas/psicología , Saliva/metabolismo , Autoinforme , Fumar/epidemiología , Fumar/metabolismo , Estados Unidos/epidemiología
18.
J Pediatr Psychol ; 42(6): 679-688, 2017 07 01.
Artículo en Inglés | MEDLINE | ID: mdl-28169405

RESUMEN

Objective: To prospectively examine dose-response and timing effects of prenatal (PTE) and postnatal tobacco exposure on obesity risk assessed by conditional weight-for-length gain (CWFLG), by 2 years of age. CWFLG over the first 2 years of life was examined for 117 PTE and 57 nonexposed children. Repeated assessments of PTE were conducted beginning in the first trimester of pregnancy, using multiple methods. PTE or postnatal exposure status was not predictive of CWFLG. However, there was a dose-response association and an association with fetal exposure ascertained by infant meconium positive for nicotine and metabolites. PTE is related to restricted growth at birth, yet associated with accelerated CWFLG by 2 years of age, a measure that controls for birthweight differences. Results highlight the importance of examining dose-response and timing of exposure associations, along with the importance of obesity risk-reduction interventions within the first 2 years of life among PTE children.


Asunto(s)
Estatura , Obesidad Infantil/etiología , Efectos Tardíos de la Exposición Prenatal/etiología , Contaminación por Humo de Tabaco/efectos adversos , Aumento de Peso , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Estudios Longitudinales , Masculino , Obesidad Infantil/diagnóstico , Embarazo , Efectos Tardíos de la Exposición Prenatal/diagnóstico , Estudios Prospectivos , Factores de Riesgo
19.
Addict Behav ; 69: 55-58, 2017 06.
Artículo en Inglés | MEDLINE | ID: mdl-28131933

RESUMEN

BACKGROUND: Approximately one in five adults engage in heavy episodic drinking (HED), a behavior with serious health and social consequences. Environmental, intrapersonal, and interpersonal factors contribute to and perpetuate HED. Prior research supports the partner influence hypothesis where partners influence each other's HED. OBJECTIVES: We examined the partner influence hypothesis longitudinally over three years in heterosexual couples in serious romantic relationships, while exploring possible sex differences in the magnitude of partner influence. METHODS: One-hundred-and-seventy-nine heterosexual couples in serious relationships (38.5% married at baseline) completed a measure of HED at baseline and again three years later. RESULTS: Using actor-partner interdependence modelling, results showed actor effects for both men and women, with HED remaining stable for each partner from baseline to follow-up. Significant partner effects were found for both men and women, who both positively influenced their partners' HED over the three-year follow-up. CONCLUSIONS: The partner influence hypothesis was supported. Results indicated partner influences on HED occur over the longer term and apply to partners in varying stages of serious romantic relationships (e.g., cohabiting, engaged, married). Women were found to influence their partners' HED just as much as men influence their partners' HED. Findings suggest HED should be assessed and treated as a couples' issue rather than simply as an individual risky behavior.


Asunto(s)
Consumo Excesivo de Bebidas Alcohólicas/psicología , Parejas Sexuales/psicología , Adulto , Femenino , Humanos , Estudios Longitudinales , Masculino , Distribución por Sexo
20.
Infant Behav Dev ; 45(Pt A): 1-10, 2016 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-27543942

RESUMEN

This study examined the association between fetal tobacco exposure (FTE) and focused attention at 9 months of child age, and the role of child sex and infant behavioral reactivity as potential moderators of this association. Data were obtained from 203 mothers and their infants (105 fetally exposed and 98 non-exposed) on infant focused attention and behavioral reactivity to a frustration task. FTE was ascertained via nicotine metabolites in infant meconium, reflecting primarily third trimester fetal exposure. Results demonstrated a main effect of FTE on focused attention, such that exposed infants exhibited lower levels of focused attention than non-exposed infants. Behavioral reactivity, but not infant sex, moderated the relationship between FTE and focused attention, such that exposed infants who were highly reactive to frustration had the lowest levels of focused attention. Results suggest that smoking interventions, even in the third trimester, may have a positive impact on attentional outcomes for infants.


Asunto(s)
Atención/fisiología , Conducta del Lactante/fisiología , Genio Irritable/fisiología , Nicotiana/efectos adversos , Efectos Tardíos de la Exposición Prenatal/inducido químicamente , Efectos Tardíos de la Exposición Prenatal/fisiopatología , Femenino , Humanos , Lactante , Masculino , Embarazo
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